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Acrobat
Uploaded Dec 23, 2009
SCLC is one of the two major types of lung cancer, and although it used to be taught as comprising 25% of lung cancer cases, in the last 15 years that has dropped to 20%, then 15%, and now below th... more
Acrobat
Uploaded Dec 23, 2009
While progress in small cell lung cancer (SCLC) has been slow, over the past few years there have been leads in management of extensive disease that have introduced a potential change in the standa... more
Acrobat
Uploaded Dec 23, 2009
Prophylactic Cranial Irradiation (PCI) is established as a treatment approach for patients with LD-SCLC who have had a complete or “good partial” response to chemo and radiation.
Acrobat
Uploaded Dec 23, 2009
The value of maintenance therapy has been tested in ED-SCLC, where treatment with initial standard doublet chemo was followed immediately by single-agent “maintenance chemotherapy”, in hopes of del... more
Acrobat
Uploaded Dec 23, 2009
SCLC is typically sensitive to chemo and radiation initially, but it tends to be considerably less responsive after recurrence. Unfortunately, most SCLC patients, or about 75-80% of patients with L... more
Acrobat
Uploaded Dec 23, 2009
Patients with SCLC very often have a nice response to chemo, so much so that we can often tell by how a person is doing clinically that they’re responding. They may start gaining weight after weeks... more
Acrobat
Uploaded Dec 23, 2009
he treatment of relapsed SCLC isn’t especially controversial, because this is an area where there aren’t enough breakthroughs. In someone fit enough to perform their own activities of daily living ... more